He was one of the most celebrated sportsmen of the 20th century - the first boxer to win the world heavyweight title three times.
But his global standing has been earned as much from his work outside the ring, as in.
He called himself "The Greatest" and few disagreed.
After a legendary boxing career of 20 years, Muhammad Ali was diagnosed with Parkinson's disease in the mid-1980s.
Despite the increasingly aggressive neurological disease, he continued to raise millions of dollars for charity and inspire communities.
He travelled the world in support of the downtrodden, gaining their admiration and of world leaders alike.
But he lost the ability to speak along with his famous wit as his illness got steadily worse.
The frequency of his hospital stays increased recently and he died in hospital in Phoenix, Arizona.
So, how will the world remember Muhammad Ali?
Presenter: Martine Dennis
Chris Eubank - Former middleweight world champion
Michael Kirtley - Ali's friend and international feature writer
Marc Spears - Sports writer
Source: Al Jazeera