Maradona, who died in November aged 60, had taken seven different medicines to treat depression, anxiety and other ailments but “there was no presence of [illegal] drugs,” a judicial official told the Reuters news agency.
The autopsy, which was based on blood and urine samples and released by the Buenos Aires Scientific Police, said Maradona had problems with his kidneys, heart and lungs.
Investigators are looking into various facets of his death that rocked Argentina and the wider footballing world and have not ruled out wrongful death.
The more detailed autopsy confirmed the results of one carried out immediately after his death that said the former Boca Juniors and Napoli player died from “acute pulmonary edema secondary to exacerbated chronic heart failure with dilated cardiomyopathy.”
In an angry broadside at her father’s critics, Maradona’s daughter Gianinna said the autopsy showed “a result compatible with cirrhosis of the liver”.
The charismatic 1986 World Cup winner, who was regarded as one of the greatest football players of all time, had battled alcohol and drug addiction for much of his life.
A judge last week ruled that Maradona’s body cannot be exhumed or cremated in case DNA is needed at a later date for use in paternity or other cases.
Maradona has five recognised children and six with filiation requests. They are part of a complex inheritance process under way in Argentina.