Two Israeli missiles struck targets near Damascus airport early on Tuesday, Syrian state media said.
The Syrian state news agency, Sana, said “two Israeli missiles came down near Damascus international airport”.
Syrian opposition sources told DPA news agency that the midnight attack targeted an Iranian cargo plane, which was landing at Damascus International Airport.
When contacted by AFP news agency, a spokesman for the Israeli army said: “We do not comment on foreign reports.”
Israel has warned of a growing Iranian military presence in neighbouring Syria, which it sees as a threat to its safety.
Its military has carried out attacks on Iranian and Iran-affiliated targets in Syria since April of this year.
Iran has vowed retaliation for one alleged Israeli attack on April 30 that reportedly killed a number of Iranian personnel.
Iran and their Hezbollah-backed movement have been fighting alongside Syrian government forces since the conflict started in 2011.
Israeli seized a large swathe of the Golan Heights from Syria in the 1967 Six-Day War and later annexed it, in a move never recognised by the international community.