Starting on Tuesday, 115 cardinals from around the world will gather at the Sistene Chapel for a secret meeting to elect the next Pope.
One of the biggest issues the next Pope will face is how to modernise a faith that many believe is out of touch with the modern world.
Benedict XVI, an intellectual at heart, was often seen as out of touch.
Al Jazeera's Hoda Abdel Hamid reports from Rome.
Source: Al Jazeera