Spanish world champion Marc Marquez became the first man in 17 years to win 10 consecutive MotoGP races when he rode to a comfortable victory at Indianapolis.
Not since Australian Mick Doohan won 10 in a row in 1997 had a rider put together that long a streak.
Marquez, riding a Repsol Honda, completed the 27 laps (112.6km) in 42 minutes, 7.041 seconds, 1.803 seconds ahead of compatriot Jorge Lorenzo (Yamaha).
Italian Valentino Rossi (Yamaha) was 6.558 seconds back in third place, with Spaniard Dani Pedrosa (Honda) fourth in an action-packed race that featured several crashes.
Marquez, 21, also increased his lead in the 2014 standings, picking up 25 points to improve to a perfect 250 points for the season.
Pedrosa is second on 161 points, with seven-time world champion Rossi close behind on 157 points after 10 of 18 races.