Defending champions Juventus stretched their Serie A unbeaten streak to 46 games with a 2-1 victory at Siena on Sunday.
Claudio Marchisio scored what proved to be the winner for the league leaders six minutes from time.
Andrea Pirlo gave Juventus the lead with a trademark free kick in the 13th minute but Emanuele Calaio levelled in first-half stoppage time, with Juventus looking lethargic. Pirlo also hit the crossbar with another free kick.
Juventus coach Antonio Conte was given a rousing reception by the Siena fans as he took his seat in the stands. Conte led Siena to promotion in 2011 before quitting to take over Juventus.
Conte saw his 10-month ban for match-fixing violations during his time at Siena reduced to four months on appeal this week.
Juventus took the lead through Pirlo's low free kick, which Siena goalkeeper Gianluca Pegolo got a hand to but could not prevent from going in.
Pirlo almost scored from another set piece in the 39th minute but crashed his effort off the crossbar.
Juve came close to doubling their lead two minutes from halftime but Pegolo pulled off a good save to keep out Marchisio's screamer.
Siena levelled moments later as Calaio was left completely unmarked to head in Angelo's cross.
Sebastian Giovinco had a hand in the winner as his cross was headed out but only as far as the onrushing Marchisio, who volleyed it into the bottom right corner.
Napoli remain joint top with Juventus after beating Udinese 2-1.
Marek Hamsik and Goran Pandev scored in the first half, either side of Giampiero Pinzi's leveller.
The defeat leaves Udinese, who were at one point title contenders last season, languishing in the bottom half.
Ten-man Inter Milan hung on to beat crosstown rival AC Milan 1-0 in a bad-tempered derby.
Walter Samuel headed Inter in front in the fourth minute following a howler from goalkeeper Christian Abbiati as the Nerazzurri's quick start seemed to surprise Milan.
Milan improved but had Riccardo Montolivo's goal disallowed for a foul on Inter goalkeeper Samir Handanovic.
Inter's chances of a third straight derby victory took a hit when Yuto Nagatomo was sent off for a second yellow card shortly after the break. Milan laid seige to the Inter goal but could not find the equaliser, despite going agonisingly close on several occasions.
Also Sunday, high-flying Lazio cruised to a 3-0 win at struggling Pescara.
Hernanes opened the scoring with a stunning 30-yard free kick in the fifth minute, and Miroslav Klose dribbled round Pescara goalkeeper Mattia Perin in the 25th to double Lazio's lead before scoring his fifth goal of the season with a powerful downwards header 10 minutes later.
In the lunchtime fixture, American Michael Bradley scored his first goal for Roma in a 2-0 win against Atalanta.
The United States midfielder sealed the game in the 62nd minute, slotting in the ball after Atalanta goalkeeper Andrea Consigli spilled Mattia Destro's powerful effort.
Erik Lamela gave Roma the lead on the half hour, playing a smart one-two with Francesco Totti before slotted it past the onrushing Consigli.
Stevan Jovetic continued his impressive start to the season as he scored his fifth goal of the season to send Fiorentina on their way to a 1-0 victory against Bologna.
Catania also got off to a good start in their 2-0 win against 10-man Parma as Alejandro Gomez gave them the lead with less than two minutes on the clock.
Parma defender Yohan Benalouane was sent off midway through the second half for a second bookable offence.
Gonzalo Bergessio sealed the result 10 minutes from time and could have doubled his tally in stoppage time but his effort was disallowed for offside.
Elsewhere, Cagliari's new coaches Ivo Pulga and Diego Lopez got their reign off to a perfect start, recording the Sardinian team's first victory of the season with a 1-0 win at Torino.