Defending UEFA Champions League champion AC Milan will be satisfied with their draw for the group stage of the competition, while Manchester United and Chelsea will revisit quarterfinal rivals.
Milan claimed their seventh European title in May with a 2-1 win over Liverpool.
They were drawn in Group D with Benfica, Celtic and Shakhtar Donetsk.
Manchester United will face AS Roma in Group F, along with Sporting and Dynamo Kiev.
United beat AS Roma 7-1 at Old Trafford in the second leg of last season's quarterfinals, a night which manager Alex Ferguson called his greatest in European soccer.
Chelsea and Valencia played in another quarterfinal last season, and the Blues won with 90th-minute goal from Michael Essien in the second leg.
Joining them in Group B are Schalke and Rosenborg.
The Group of Death
FC Barcelona, the 2006 champion, were drawn in Group E with six-time defending French champion Lyon, Stuttgart and Rangers.
Five-time champion Liverpool was drawn in Group A alongside 2004 winner FC Porto, Marseille and Besiktas.
Real Madrid were joined in Group C by Werder Bremen, Lazio and Olympiakos.
Inter Milan, PSV Eindhoven, CSKA Moscow and Fenerbahce were drawn into Group G.
Arsenal, finalists in 2006, have 1986 champions Steaua Bucharest and Slavia Prague in Group H.
Slavia Prague beat four-time champions Ajax in qualifying.
The final spot in the group will go to either Sevilla or AEK Athens.
The two play the second leg of their series on Monday.
The match was postponed because of the death of Sevilla midfielder Antonio Puerta and the devastating forest fires in Greece.
Sevilla, which has won back-to-back Uefa Cup titles, leads 2-0 and also plays AC Milan in the Super Cup on Friday in Monte Carlo.