It was perhaps not surprising that Bonds would have a unhappy evening given he has hit only three home runs in 77 at-bats since Petco Park opened in 2004.
Shouts of derision
The 43-year-old leftfielder received shouts of derision from the stands each time he headed to the plate.
While anti-Bonds signs were confiscated at Dodger Stadium in Los Angeles earlier in the week, plenty of fans held up signs showing an asterisk at Petco Park.
Bonds remained stuck on 754 career home
runs for a sixth straight game [GALLO/GETTY]
Many believe that Bonds has used performance-enhancing drugs during his career, including steroids, and argue his home run total should be accompanied by an asterisk in baseball record books and that Aaron's notation should remain unblemished.
Sensing trouble should Bonds reach the record more than 20 security guards circled the playing field between innings.
One player not struggling to go and find his range was San Diego leftfielder Scott Hairson, who landed his second homer of the game in the bottom of the 10th to give the hosts a 4-3 win.
The Giants have two more games in San Diego over the weekend before returning to San Francisco on Monday for matches against the Washington Nationals and the Pittsburgh Pirates.