The war on drugs was launched in 2006 - and the president and his predecessor made it a priority.
Some cartel leaders have been captured or killed but that hasn't deterred other traffickers.
Now, cartels are brazenly challenging the armed forces. A new cartel, the Jalisco New Generation, recently shot down an army helicopter, killing three and injuring others.
But does the government really have a strategy to deal with the drug cartels? Or is it simply being outdone?
Presenter: Mike Hanna
Alejandro Hope- Security analyst and former intelligence officer at the Center for Investigation and National Security.
Guillermo Trejo- A politically engaged Mexican artist.
Laura Carlsen- Director of the Americas programme at the Center for International Policy.
Source: Al Jazeera