The killing of Osama bin Laden by US forces on Pakistani soil, has further inflamed tensions between the two nations. It is a relationship that for years, has been marred by mistrust.
Paul Brennan, US counter terrorism chief said it was inconceivable that bin Laden did not have some support in Pakistan; a claim strenuously denied by Pakistani authorities.
Although it may be too early to tell whether it was incompetence or complicity on Pakistan's part, the US' 10-year alliance with the country is now in question.
Just what impact will this have on the two countries? And will the US ever trust Pakistan in its war against al- Qaeda?
Inside Story, with presenter Jane Dutton, discusses with Omar Waraich, a Pakistan-based journalist for The Independent newspaper; Shiraz Maher, a senior fellow at the International Centre for Study of Radicalization at King's College; and Christine Fair, and author and associate professor at the Center for Peace and Security Studies at Georgetown University.
This episode of Inside Story aired from Tuesday, May 3, 2011.