Ketziot is set up like a military camp, with security prisoners quartered in tents rather than buildings.
In Monday's riot, prisoners set 10 tents on fire and attacked the guards, wounding 15 of them, Domnitz said.
Prison officers moved in to quell the riot, injuring 15 prisoners, he said.
Four prisoners were hospitalised, with one critically wounded by a "non-lethal weapon", Domnitz said.
"The weapon was used in response to the endangerment of the lives of prison officers in the cell block," he said.
In the West Bank, Nabil Abu Rdeneh, a spokesman for Mahmoud Abbas, the Palestinian president, accused Israel of conducting a "repression campaign" against the prisoners.
He said the prison guards had used clubs, stun grenades and tear gas to disperse the crowd and said 250 people were injured.