Officials say at least 10 fighters linked to the Taliban and al-Qaeda have been killed by Pakistani troops in the tribal region of Bajaur.
Six people suspected of planning an attack on a security post were killed late on Monday in a mortar attack on their vehicle in the town of Loisam, a Pakistani security official said on Tuesday.
Four fighters were also killed as troops repelled an attack on a nearby checkpost, a local government official said.
The casualty figures could not be independently verified.
News of the deaths comes days after a massive truck bomb attack on the Marriott Hotel in the Pakistani capital Islamabad left at least 53 people dead.
Pakistani troops backed by helicopter gunships have been operating in the Bajaur region, which lies close to the border with Afghanistan, since last month.
Analysts have said that the attack on the five-star hotel, which is popular with foreign tourists and diplomats, could have been carried out in response to the military operations in Bajaur.
Al-Qaeda connection
Pakistani officials have said that the attack on the Marriott Hotel was carried out by an al-Qaeda cell based in Islamabad.
At least 800 people, mostly opposition fighters, have been killed so far during the campaign in Bajaur.
Islamabad has come under increasing pressure to combat fighters linked to al-Qaeda and the Taliban in Pakistan's tribal regions.
The fighters, who have carried out a string of suicide bombings in the country, are also accused of attacking US and Nato forces in neighbouring Afghanistan.
Washington has said that violence in Afghanistan appears to have reduced since the Pakistani military operation in Bajaur began.
But a string of US cross-border operations in Pakistan tribal regions against Taliban and al-Qaeda linked fighters have been called a threat to the country's sovereignty by Asif Ali Zardari, Pakistan's president.
Zardari is expected to discuss the cross-border attacks with George Bush on Tuesday on the sidelines of the UN General Assembly in New York.
BA cancellations
Meanwhile, in a development believed to be related to the Marriott Hotel bombing, British Airways said on Tuesday that it had "indefinitely" cancelled all flights to the Pakistani capital.
BA issued a statement confirming the cancellation of its six weekly services to Islamabad, the only destination it flies to in Pakistan, a day after saying that it was only temporarily suspending flights.
"In light of the security situation in Pakistan, British Airways has cancelled its flights from Islamabad to Heathrow indefinitely," the statement said.