Earlier this year Roddick announced she was suffering from liver damage caused by the Hepatitis C virus she contracted following a blood transfusion more than 35 years ago.
She subsequently launched a campaign supporting those with the disease.
Roddick, a multi-millionaire who championed human rights and environmental concerns, founded The Body Shop in Brighton, southern England, in 1976, selling toiletries made from natural ingredients.
The Body Shop has grown into
a global cosmetics empire [EPA]
Her brand established a global trend for eco-business long before green issues took centre stage around the world.
She also sought to encourage development by purchasing materials from small communities in the developing world and championed recycling in Body Shop stores.
Roddick said it was her mother's frugality during World War Two that inspired her to campaign for environmental issues and question retail conventions.
"Why waste a container when you can refill it? And why buy more of something than you can use? We behaved as she did in the Second World War, we reused everything, we refilled everything and we recycled all we could," Roddick wrote.
Her business grew into more than 2,000 stores serving more than 77 million customers in 51 different markets.
Roddick sold her stake in The Body Shop to France's L'Oreal last year.